Dr. Yanli Wang

Dr. Yanli Wang

Principal Investigator
Institute of Biophysics
Chinese Academy of Sciences
BioGRAPHY

Yanli Wang is a professor in Institute of Biophysics, Chinese Academy of Sciences, and a HHMI International Research Scholar. Prof. Wang has completed her PhD from University of Science and Technology of China and postdoctoral studies from Memorial Sloan-Kettering Cancer Center. Prof. Wang's group interests in understanding how small regulatory RNA or DNA mediates prokaryotic defense against invasion by foreign nucleic acids. The main focus of her work is to systematically demonstrate the mechanisms of the CRISPR-Cas system, and Ago protein-mediated DNA interference.

Speaker's Schedule

Dec 22, 2022
07:40 - 08:20
Society Lecture | Live from Hangzhou site
How does CRISPR-Cas9 cut DNA and be inhibited by Acrs?
CRISPR-Cas systems are adaptive immune systems of bacteria and archaea that defend against bacteriophages. To evade the threat of CRISPR-Cas systems, some bacteriophages encode anti-CRISPR (Acr) proteins. We are interested in the molecular mechanism of high-fidelity II-C Cas9 enzymes and how the Acr protein inhibits its activity.
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