Dr. Ruiming Xu

Dr. Ruiming Xu

Director & Investigator
Institute of Biophysics
Chinese Academy of Sciences
BioGRAPHY

Rui-Ming Xu received his Ph.D. degree in Physics from Brandeis University in 1990. Following post-doctoral training in physics with Steven Weinberg at UT Austin and C.N. Yang at SUNY Stony Brook, he changed his field of research to structural biology in 1993 at Cold Spring Harbor Laboratory, where he rose to the rank of Professor. He joined NYU School of Medicine as a tenured professor in 2005, and in 2008 have moved to Institute of Biophysics, Chinese Academy of Sciences, where he is currently Director and an Investigator. His research research interest has been on molecular mechanisms of eukaryotic gene repression, with particular emphasis on epigenetic inheritance and RNA processing.

Speaker's Schedule

Dec 22, 2022
14:40 - 15:00
Hangzhou Talk #21
Mechanism of de novo nucleosome assembly
Chromatin inheritance following DNA replication entails de novo nucleosome assembly by chromatin assembly factor-1 (CAF-1), which is a conserved heterotrimeric complex responsible for histone deposition at the replication fork during S-phase. We have determined the structure of CAF-1 bound to histones H3 and H4, and revealed significant insights into the process of nucleosome assembly by CAF-1.
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